They should also be advised to take immediate gynecological consultation if they find any change in the frequency of baby's movement or increased contractions after taking the drugs. If a second generation agent has to be used then loratadine or cetirizine should be preferred as they have been widely studied for possible teratogenic effects and have been found to be nonteratogenic till date.
Both these agents are pregnancy category B agents. Second generation agents are preferably used after the first trimester if it has to be and preferably avoided in the early pregnancy when organogenesis takes place.
To conclude first generation antihistamines such as chlorpheniramine, hydroxyzine, and dexchlorpheniramine are the safest among antihistamines to be used in pregnancy. Source of Support: Nil. Conflict of Interest: None declared. National Center for Biotechnology Information , U.
Journal List J Pharmacol Pharmacother v. J Pharmacol Pharmacother. Sumit Kar , Ajay Krishnan , K. Preetha , and Atul Mohankar. Author information Copyright and License information Disclaimer. E-mail: moc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.
This article has been cited by other articles in PMC. Abstract Antihistamines are one of the most common drugs that are used extensively in various dermatological and nondermatological conditions.
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Evidence to date. If you have a reaction to an insect bite, you may only need to take loratadine for a day or two.
You may need to take it for longer if you're taking it to prevent hay fever symptoms when the pollen count is high. Talk to your doctor or pharmacist if you're not sure how long you need to take loratadine for. Loratadine is unlikely to do you any harm if you take it for a long time.
However, it's best to take it only for as long as you need to. It's best not to drink alcohol while you're taking loratadine, as it can make you feel sleepy. Loratadine is classed as a non-drowsy antihistamine but it's still possible to feel sleepy after taking it.
If this happens to you, do not drive a car or ride a bike until you feel better. It's an offence to drive a car if your ability to drive safely is affected. It's your responsibility to decide if it's safe to drive. If you're in any doubt, do not drive. Talk to your doctor or pharmacist if you're unsure whether it's safe for you to drive while taking loratadine. UK has more information on the law on drugs and driving.
It's less likely to make you feel sleepy than other, so-called, sedating antihistamines such as Piriton chlorphenamine. Most people prefer to take a non-drowsy antihistamine instead of a sedating one.
An exception is when you want the medicine to make you sleepy — for example, if you have itchy skin that's keeping you awake. Other non-drowsy antihistamines like cetirizine , desloratadine, fexofenadine and levocetirizine seem to work as well as loratadine.
However, loratadine, desloratadine and fexofenadine seem to be less likely to make you feel sleepy than cetirizine. Yes, you can take loratadine together with paracetamol or ibuprofen.
Sometimes, doctors recommend that people with a severe, itchy skin rash take 2 different antihistamines together for a few days. As well as taking a non-drowsy antihistamine like loratadine during the day, your doctor may tell you to take a sedating antihistamine at night if the itching is making it difficult to sleep.
Yes, it's fine to take loratadine together with some other types of hay fever treatment, including steroid nasal sprays such as Beconase, Rhinacort Aqua and Flixonase Nasules , or eyedrops. Your doctor might suggest you or your child take a higher dose of loratadine up to 4 times the usual dose for severe itchy skin rash or swelling underneath the skin angioedema.
There's no evidence to suggest that taking loratadine will reduce fertility in either men or women. However, speak to a pharmacist or your doctor before taking it if you're trying to get pregnant. Loratadine will not affect any type of contraception, including the combined pill or emergency contraception.
It will help if you do not spend too much time outside if the pollen count is high. Page last reviewed: 14 October Next review due: 14 October Loratadine Clarityn On this page About loratadine Key facts Who can and cannot take loratadine How and when to take loratadine Side effects How to cope with side effects of loratadine Pregnancy and breastfeeding Cautions with other medicines Common questions about loratadine.
About loratadine Loratadine is an antihistamine medicine that helps with the symptoms of allergies. It's used to treat: hay fever conjunctivitis red, itchy eyes eczema hives urticaria reactions to insect bites and stings some food allergies Loratadine is known as a non-drowsy antihistamine.
It comes as tablets or as a liquid that you swallow. Help us improve our website Can you answer a quick question about your visit today? You'll usually take loratadine once a day. Loratadine is classed as a non-drowsy antihistamine, but some people still find it makes them feel slightly sleepy.
Children may have a headache and feel tired or nervous after taking loratadine. It's best not to drink alcohol while you're taking loratadine as it can make you feel sleepy.
Adults and children aged 2 years and older can take loratadine. To make sure it's safe for you, tell your doctor or pharmacist before taking loratadine if you: have ever had an allergy to loratadine or any other medicines have severe liver failure have an allergy to food additives have epilepsy or another illness that puts you at risk of seizures or fits are due to have an allergy test — taking loratadine may affect the results, so you might need to stop taking it a few days before the test.
The usual dose in adults is 10mg once a day. Doses are usually lower for people with liver problems. How to take it Loratadine comes as 2 different types of tablet: ordinary and melt-in-the-mouth tablets.
You can take loratadine with or without food. When to take it You may only need to take loratadine on a day when you have symptoms, for instance if you've been exposed to a trigger such as animal hair.
What if I forget to take it? Do not take 2 doses to make up for a forgotten dose. What if I take too much? Urgent advice: Contact for advice if:.
Common side effects The most common side effect of loratadine is feeling sleepy. Side effects in children may include: headaches feeling tired or nervous Serious allergic reaction In rare cases, loratadine may cause a serious allergic reaction anaphylaxis.
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